You can find four key dilemmas are talked about in thymus surgery today the role of minimally invasive surgery, the part of lymph node dissection, extension of resection in the case of nonmyasthenic thymoma, remedy for locally advanced tumors for the thymus with pleural defeats. A retro- and prospective analysis of this outcomes of minimally unpleasant surgery was carried out in 18 patients with thymic tumors within our study, just who got medical treatment during 2018 and 2021 into the department of thoracic surgery (,,New Hospitals“, Tbilisi, Georgia). The average age of patients had been 51.4±13.2 (M±SD), 3 males (22.2%), 15 females (77.8%). All clients were done thymectomy by videothoracoscopic method, there were no postoperative crises of myasthenia gravis and other problems whatever the case. Research results display high efficiency minimally invasive thymus surgery in hospital practice, which be of assist to optimal administration and enables to reduce the socio-economic running on wellness service.The goal of our potential study is always to compare and evaluate the outcome of two treatments of left-sided malignant colon obstruction Hartmann’s process (HP) and Resection with primary anastomosis (RPA). 90 clients with diagnosis of left-sided malignant colon obstructions had been enrolled in this research. The patients were assigned into two groups Hartmann’s process (HP) team and Resection and main anastomosis group (RPA). Several medical attributes had been determined and contrasted between your groups hospital stay times, length of the surgery, postoperative problems (during 1 month after surgery) and mortality was evaluated. 37 patients had been signed up for the Hartmann’s procedure (HP) team and 53 clients were enrolled in the principal anastomosis (RPA) team and had undergone various kinds of colon resections with primary anastomosis. There was clearly 1mortality in HP group and 1 in RPA group. In RPA team, there have been 7 problems (13.2%). 1 intraabdominal abscess after colorectal anastomosis, that was healed with antibiotic therapy and percutaneous drainage; 5 instances of wound attacks, 1- leak of colorectal anastomosis as well as in Hartmann’s treatment team there have been 8 (21.6%) problems (7 – wound infections, 1-necrosis of colostomy). But this huge difference just isn’t statistically reliable (p=0.110). In stenting RPA stay were – 6 times and in HP group, it absolutely was 8 days. This huge difference is statistically dependable (P=0.02). In case there is left-sided cancerous colon obstructions, Primary anastomosis input ought to be preferred, instead of Hartmann’s procedure. As time goes by it really is necessary to do the randomized tests, that will learn the lasting results (recurrence of cancer, success price) of the treatment method.Aim – in customers with knee meniscus injury, contrast the therapeutic effectiveness for the use of meniscus suturing with anterior cruciate ligament (ACL) surgery with meniscus resection in conjunction with anterior cruciate ligament surgery to enhance the treatment of such pathologies. The study examined customers (n=66) with knee meniscus damage who obtained surgical procedure when you look at the traumatology department of the State Budgetary Healthcare organization regarding the Moscow area „City Clinical Hospital № 12 of the Moscow City wellness division“. The customers were randomized by gender, age, clinical, biochemical and instrumental data and split into 2 groups. The initial group (n=33) – patients underwent resection of the anterior meniscus with simultaneous plasty of the anterior cruciate ligament (in 17 (51.6%) – medial, plus in 16 (48.4%) – lateral), age group was 26.8±6.33 many years, the percentage of men was 19 (57.6%), and women – 14 (42.4%). The second group (n=33) – patients underwent suturing for the meniscus wite above indicates that arthroscopic stitching shows large dependability of use into the rupture of this meniscus of this knee joint.This study aimed to evaluate the results of treatment of customers with anterolateral chronic instability after arthroscopic stabilization of this ankle joint utilizing anchor fixators, to determine the risk factors for the recurrence of instability after surgery and methods of their particular diagnosis. The research involved 28 customers from 2016 to 2020. carried out 28 arthroscopic operations for chronic lateral uncertainty. The Arthroscopic Brostrom-Gould procedure ended up being done. 22 customers were females and 6 were males. The typical chronilogical age of the individual was 38.6 years (22-55 years). Ankle arthroscopy ended up being carried out making use of a shaver, an ablator, and an anchor fixator. All the customers had been discharged 24 hours later; immobilization associated with ankle joint within the orthosis ended up being 6 days as soon as of surgery. The results were assessed because of the AOFAS (United states Orthopedic Society for Foot and Ankle Surgical treatment) scale and VAS – a visual analog scale made to measure the power of discomfort, then the patient’s condition combretastatina4 inhibitor ended up being assessed. The common followup had been 58.4 months. The AOFAS scores considerably enhanced from a postoperative mean of 52.6 to 98.6 at the last grade (p˂0.005). All clients tend to be content with the result of the procedure. The results regarding the VAS scale were on average 6-8 things. Arthroscopic Brostrom-Gould procedure seems become a safe and effective medical way for treating persistent lateral uncertainty of the foot joint.Parabiosis is a well-established method to facilitate a shared blood circulation between two conjoined animals. In certain, the pairing of mice of dissimilar ages, termed heterochronic parabiosis, has been used extensively for differentiating mobile independent and non-autonomous components of aging. Evaluation of heterochronic parabionts also has assisted to determine individual circulating factors that will behave as either pro- or anti-geronics. Heterochronic parabiosis also offers proven to be an invaluable experimental system to guage the results of specific hallmarks of aging in the means of aging. As an example, heterochronic parabiosis was used recently to look at whether mobile senescence had been driven via cellular autonomous and/or non-autonomous mechanisms.