Rab1A, a member of the Ras-like protein in rat brain (Rab) family, acts as an oncogene in a variety of malignant tumors. Previous studies reported that Rab1A was highly expressed in GC tissues. However, the function and molecular mechanism of Rab1A in gastric cancer (GC) development remain far from being addressed. Rab1A mRNA and protein levels…[Weiterlesen]

BACKGROUND Endolog is an intra-medullary titanium device used for a minimally-invasive hallux valgus correction. The aim of this study was to evaluate clinical and radiographic outcomes of this device. METHODS A retrospective study with a prospective data collection was conducted. Patients underwent to Endolog procedures from September 2009 to…[Weiterlesen]

We also show that pharmacological inhibition of lactate dehydrogenase is able to reduce glucose-induced shifts towards aerobic glycolysis. This method is timely given the recent advances in our understanding of new respiratory epithelial subtypes that can only be generated in vitro through culture at ALI and will open new avenues to measure…[Weiterlesen]