The general anesthetic etomidate, which acts through GABAA receptors, impairs the formation of new memories under anesthesia. This study addresses the molecular and cellular mechanisms by which this occurs. Here, using a new line of genetically engineered mice carrying the GABAAR β2-N265M mutation, we tested the roles of receptors that…[Weiterlesen]

109-0.955). Upon selecting 9 radiomic features, we found that the logistic regression-based prediction model performed the best (AUC = 0.96, P  less then  0.001). In the external cohort, our radiomic signature showed an AUC of 0.85, which outperformed both the clinical model (AUC = 0.38, P  less then  0.001) and the radiomics-nomog…[Weiterlesen]

oor showing that only 32% of FBDGs are „recommended for use with modifications“. Our results highlight the need to revise, systematize and improve FBDG development processes in Spain.

Vitamin D deficiency remains a global public health issue, particularly in minority ethnic groups. This review investigates the vitamin D status (as measured by…[Weiterlesen]